Parents can pave a fruitful way to health for their children -- even before
their birth, studies suggest.
If mouse research conducted at Washington University School of Medicine
in St. Louis holds any water, moms-to-be at risk of premature delivery
may want to consider drinking pomegranate juice to help reduce the risk
of brain damage in their babies.
The so-called hypoxic ischemic injury -- which stems from low oxygen and
reduced blood flow and can lead to seizures, a degenerative condition known
as hypoxic ischemic encephalopathy, cerebral palsy and other abnormalities
-- occurs primarily in premature infants born before 34 weeks of gestation.
In experiments that mimicked the condition in newborn mice, investigators
found rodents whose mothers drank water mixed with pomegranate concentrate
during the last trimester of pregnancy and the first seven days of post-birth
suckling lost 60 percent less brain tissue than those whose mothers drank
sugar water or other fluids.
They also showed 84 percent less activity in an enzyme implicated in cerebral
destruction.
"Hypoxic ischemic brain injury in newborns is very difficult to treat,
and right now there's very little we can do to stop or reverse its consequences,"
said Dr. David Holtzman, head of neurology and senior author of the study,
published in Pediatric Research and supported by pomegranate fruit and
juice producer POM Wonderful.
"Most of our efforts focus on stopping it when it happens, but if we could
treat everyone who's at risk preventively, we may be able to reduce the
impacts of these kinds of injuries."
Another study, by researchers at the University of California, Berkeley,
takes the protective process back even further. The analysis, published
in Cancer Causes and Control, indicates beefing up on protein and produce
before pregnancy may reduce a woman's risk of giving birth to a baby who
will develop leukemia, the most common childhood cancer in the United States.
Upon inspection, the team discovered beef, beans and other protein-rich
fare are laden with glutathione, an antioxidant thought to help thwart
cancer by synthesizing and repairing the genetic material DNA and detoxifying
certain harmful compounds.
In protective produce, the scientists zeroed in on carotenoids -- plentiful
in carrots, string beans and cantaloupe -- as a potential anti-cancer agent.
"These findings show how vital it is that women hoping to get pregnant,
as well as expectant moms, understand that critical nutrients in vegetables,
fruit and foods containing protein, such as meat, fish, beans and nuts,
may protect the health of their unborn children," said nutritional epidemiologist
Christopher Jensen.
The nurturing role of nutritious food continues as the baby grows and develops.
"Children with healthier diets are less likely to be sick or overweight,
and they are more likely to continue healthy eating habits when they become
adults," said Sibylle Kranz, assistant professor of nutritional sciences
at Pennsylvania State University.
Her study, published in the American Journal of Public Health, showed although
the overall diet of American preschoolers improved marginally in the past
20 years, it still rings up a deficit in the produce department.
In its recently rebuilt Food Guide Pyramid, the federal government encourages
children ages 4 to 8 to down 1.5 cups of vegetables a day, an amount that
increases to 2 cups for girls ages 9 to 13 and 2.5 cups for their male
counterparts.
On the fruit side, 1.5 cups may suffice for all those age groups.
How well the guidelines are followed may depend upon such factors as proximity
to a supermarket, suggests a study conducted by Tulane University investigators
and published in Public Health Nutrition.
"If it's close by, people seem to eat more fruits and vegetables, but if
it is over 5 miles away, consumption of fruit is significantly less," said
lead author Diego Rose. "People in the United States don't eat enough
fruits and vegetables, so neighborhood environmental factors, like access
to a supermarket, or other plentiful source of low-cost fruits and vegetables,
may be important for increasing consumption, especially among low-income
households."
Proximity to restaurants seems to have the opposite effect, with those
who frequently eat out being more likely to skimp on fresh produce than
those who dine at home, according to researchers who found 73 percent of
the young Missouri families they studied failed to meet the government
guidelines.
"The more often parents eat out, the lower their intake of fruits and vegetables,"
said Amanda Harrod, a researcher at the St. Louis University School of
Public Health who presented the findings at an American Public Health Association
conference.
As parents do, so children follow.
In a study of 180 girls, at ages 7 and 9, published in the Journal of the
American Dietetic Association, researchers at Appalachian State University
found mothers partial to fruits and vegetables are less likely to pressure
their daughters, who, in turn, will be less inclined to become picky eaters
or produce shunners.
The authors cautioned caregivers to "focus less on 'picky eating' behaviors
and more on modeling fruit and vegetable consumption for their children."
Researchers also issued a caveat to parents who use aliments to assuage
ailments, often without consulting their pediatrician.
In looking at the fruitfulness of treating children's recurrent urinary-tract
infections with cranberries, the team at Brenner Children's Hospital at
Wake Forest University Baptist Medical Center found only 23 percent of
parents who subscribe to the popular practice do so with their pediatrician's
knowledge.
"It has become clear that parents frequently use cranberry for therapeutic
purposes -- occasionally in lieu of standard therapy," said Dr. Kathi Kemper,
a pediatrician and author of the report published in the journal Ambulatory
Pediatrics.
"Research to address efficacy and safety issues is needed even more urgently
than we originally thought."
Children's health can get a boost from eating fruitful fare, but there
are times, when illness strikes, it needs a doctor's care.
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Copyright
2005 by United Press International.
All
rights reserved.
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