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Volume 10, Issue 26 - February 25, 2009
Short-term high-fat diet may inflame

 

CINCINNATI, Feb. 19 (UPI) -- U.S. researchers, in an animal study, link high-fat diets -- even short-term -- to inflammation that can lead to heart disease.

The study, published in Circulation Research, finds the fat cells surrounding the coronary arteries become highly inflamed after mice are fed a high-fat diet for only two weeks.

"This is independent of weight gain or blood lipids -- cholesterol levels," study senior author Dr. Neal Weintraub of the University of Cincinnati said in a statement.

"This is a warning to those who say there isn't a problem because their weight and cholesterol levels are under control. Lipid profiles don't hold all the answers."

Bad dietary habits can lead to a number of problems, and this suggests a high fat diet is detrimental in ways that were not previously understood, Weintraub says.

"These new findings suggest a direct link between poor dietary habits and inflammation of blood vessels, mediated by the fat cells surrounding the blood vessel wall," Weintraub says.

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