Apples for Health- Prolactin is Linked With Breast Cancer

Prolactin is Linked With Breast Cancer

U.S. medical scientists have discovered molecular evidence that possibly links the hormone prolactin with breast cancer.

Researchers at the Kimmel Cancer Center at Thomas Jefferson University found prolactin -- pituitary hormone that normally stimulates breast development and milk production -- initiates a new "signaling pathway" that may regulate the growth and survival of breast cancer cells.

The work identifies the protein Jak1 as playing a key part in prolactin signaling in breast cancer. Jak1, which belongs to the cell growth-promoting tyrosine kinase class of enzymes, could represent a new drug target for treating breast cancer, said Dr. Hallgeir Rui, a professor of cancer biology and lead investigator of the study.

The research appears in the journal Molecular Endocrinology.

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