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Volume 9, Number 21 - January 16, 2008
Study provides more breast cancer facts

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DURHAM, N.C., Jan. 17 (UPI) -- A U.S. breast cancer study might help explain why some women are at increased risk of developing both breast and ovarian cancer.

Duke University Medical Center researchers said a breast cancer gene's newly discovered role in repairing damaged DNA might also lead to more effective therapies for women with and without mutated copies of the BRCA1 gene.

"Since it was discovered in 1994, BRCA1 and its role in preventing and causing cancer has been intensely studied, and our research represents an important piece of the puzzle," said Craig Bennett, the project's lead investigator. "This study has identified an important mechanism by which BRCA1 comes into play when DNA
is damaged. We have shown that this theory holds up, not just in scientific models, but in human breast cancer cells as well."

The findings are detailed in the online journal PLoS ONE.

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Copyright 2008 by United Press International
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